Bad news in the fight against the AIDS virus: The government is halting a large U.S. study of a possible HIV vaccine because the experimental shots aren't preventing infection.
The study had enrolled about 2,500 people, mostly gay men, in 19 cities. Half received an experimental vaccine developed by the National Institutes of Health, and half received dummy shots.
A safety review this week found that slightly more volunteers who had received the vaccine later became infected with HIV. It's not clear why.
The NIH said Thursday that it is stopping vaccinations, but will continue to study the volunteers' health.
Multiple attempts at creating an AIDS vaccine have failed over the years. But researchers continue to try, pointing to modest success in a 2009 study in Thailand.
A New Taipei City Department of Environmental Protection worker sprays sterilising anti-H7N9 virus disinfectant around chicken stalls inside a market in New Taipei City April 8, 2013.Reuters
Another person died in China from a new strain of bird flu on Tuesday, state media said, bringing to eight the number of deaths from the H7N9 virus since it was confirmed in humans for the first time last month.
The 83-year-old victim, from the eastern province of Jiangsu, was admitted to hospital with a fever on March 20 and confirmed as having H7N9 on April 2, the official Xinhua news agency reported.
The H7N9 strain has infected 24 people, all of them in eastern China, of whom eight have died.
The World Health Organization has praised China for mobilizing resources nationwide to combat the strain by culling thousands of birds and monitoring hundreds of people close to those infected.
Authorities have said there is no evidence of the H7N9 strain being transmitted between humans.
The bird flu outbreak has caused global concern and some Chinese internet users and newspapers have questioned why it took so long for the government to announce the new cases, especially as two of the victims fell ill in February.
Airline shares have fallen in Europe and in Hong Kong over fears that the virus could be lead to an epidemic like Severe Acute Respiratory Syndrome (SARS), which emerged in China in 2002 and killed about 10 percent of the 8,000 people it infected worldwide.
Chinese authorities initially tried to cover up the SARS outbreak.
In the case of the H7N9 strain, authorities have said they needed time to identify the virus, with cases spread between eastern Zhejiang, Jiangsu, and Anhui provinces as well as the business hub Shanghai.
Other strains of bird flu, such as H5N1, have been circulating for many years and can be transmitted from bird to bird, and bird to human, but not generally from human to human.
Frustrated ... Arsene Wenger is outgunned by Andre Villas-Boas.Source: Adam Davy / AAP
Arsene Wenger admitted it was frustrating to lose another big game following Arsenal's defeat at White Hart Lane but rejected suggestions that Tottenham Hotspur were now the top team in North London.
The Gunners pulled a goal back when Per Mertesacker's header was deflected in but they could not salvage a point and Wenger was again left to bemoan defensive mistakes.
P
W
D
L
GD
Pts
1
Man United
28
23
2
3
37
71
2
Man City
27
16
8
3
26
56
3
Tottenham
28
16
6
6
16
54
4
Chelsea
28
15
7
6
26
52
5
Arsenal
28
13
8
7
21
47
6
Everton
28
11
12
5
9
45
7
Liverpool
28
11
9
8
19
42
8
Swansea
28
10
10
8
5
40
9
West Brom
28
12
4
12
1
40
10
Fulham
28
8
9
11
-5
33
11
Stoke
28
7
12
9
-7
33
12
West Ham
28
9
6
13
-9
33
13
Norwich
28
7
11
10
-18
32
14
Sunderland
28
7
9
12
-7
30
15
Newcastle
28
8
6
14
-11
30
16
Southampton
28
6
9
13
-12
27
17
Wigan
28
6
6
16
-22
24
18
Aston Villa
27
5
9
13
-26
24
19
Reading
28
5
8
15
-20
23
20
QPR
28
3
11
14
-23
20
"It is difficult to swallow a defeat like that because of the effort we put in," he told Sky Sports.
"We made it difficult for ourselves. They had no shots on goal and then we were down 2-0.
"We came back in the second half and dominated the game again, but it was difficult to get a flow in the final 20 minutes because there were a lot of stops and we didn't find a second goal."
The result left Arsenal five points adrift of fourth-placed Chelsea and seven behind Spurs, but Wenger is refusing to give up in the battle for Champions League qualification.
He said: "It is very frustrating but we have to put the energy in like we did today and keep going and you never know.
"It would be absolutely terrible not to fight like mad because there is a lot of positives in the game.
"What happened today we have seen repeated so many times in big games that of course it's difficult."
Questioned on whether there had been a power shift in North London, Wenger replied: "That's not the impression I got from the game today.
"We were not efficient in those decisive zones, not at the back or up front. We were not cautious enough. On the two goals we played offside in a position where we shouldn't play offside."
Meanwhile, Andre Villas-Boas hailed an important win but insisted his players would not be taking anything for granted in the race for the Champions League.
"It was very, very important for what it means, but obviously nothing is finished yet," he told Sky Sports.
"We have to believe that we still have to fight hard. We have to play Liverpool (next weekend) and we have to try to profit from another important fixture and keep doing our job.
"It is important we gather as many points as we can to finish where we want to be."
Arsenal finished strongly last season to pip Tottenham to third, with Chelsea's Champions League triumph ensuring Spurs missed out on this season's competition.
"Last year, by this time, Arsenal made the difference of seven points to Tottenham and we know how it finished," Villas-Boas added.
"Motivations are now different. We are extremely confident. They are on a low at the moment.